Pemphigus vulgaris is a rare auto-immune disorder that affects the skin and mucous membranes. In this condition, the immune system mistakenly attacks the part of the skin that attaches it to the underlying layers, leading to the formation of painful blisters and sores.

The blisters and sores in pemphigus vulgaris can be widespread and can occur on the skin, as well as inside the mouth, nose, throat, and genital areas. The condition can be painful and debilitating, affecting a person’s quality of life. Diagnosis is typically confirmed through a combination of clinical examination, biopsy, and immunological tests.

Treatment usually involves both medication to treat the skin, as well as medications to control the autoimmune response and reduce inflammation. Identifying the trigger for the immune system can help reduce the amount and severity of episodes.